Thrombosis is the formation of a blood clot (thrombus) in an unbroken blood vessel, usually a vein (but occasionally an artery), that obstructs the blood flow.

Obstruction of blood flow prevents blood circulation to tissues beyond the obstruction, leading to tissue death.

Thrombosis can be fatal, for example if the obstruction occurs in the coronary circulation of the heart. If the blood clot breaks free and travels with the blood stream it is called an embolus. This can become problematic when it reaches a blood vessel that is too small for it to fit down. The result of this could be a stroke, myocardial infarction or other issues.

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